Mechanical Entrapment Is Insufficient and Intercellular Adhesion Is Essential for Metastatic Cell Arrest in Distant Organs

In this report, we challenge a common perception that tumor embolism is a size-limited event of mechanical arrest, occurring in the first capillary bed encountered by blood-borne metastatic cells. We tested the hypothesis that mechanical entrapment alone, in the absence of tumor cell adhesion to blo...

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Bibliographic Details
Main Authors: Glinskii, Olga V, Huxley, Virginia H, Glinsky, Gennadi V, Pienta, Kenneth J, Raz, Avraham, Glinsky, Vladislav V
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2005
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501167/
https://ncbi.nlm.nih.gov/pubmed/15967104
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