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Cross-scale, cross-pathway evaluation using an agent-based non-small cell lung cancer model

We present a multiscale agent-based non-small cell lung cancer model that consists of a 3D environment with which cancer cells interact while processing phenotypic changes. At the molecular level, transforming growth factor β (TGFβ) has been integrated into our previously developed in silico model a...

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Hlavní autoři: Wang, Zhihui, Birch, Christina M., Sagotsky, Jonathan, Deisboeck, Thomas S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735669/
https://ncbi.nlm.nih.gov/pubmed/19578172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp416
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