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Cross-Scale Sensitivity Analysis of a Non-Small Cell Lung Cancer Model: Linking Molecular Signaling Properties to Cellular Behavior

Sensitivity analysis is an effective tool for systematically identifying specific perturbations in parameters that have significant effects on the behavior of a given biosystem, at the scale investigated. In this work, using a two-dimensional, multiscale non-small cell lung cancer (NSCLC) model, we...

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Detalhes bibliográficos
Main Authors: Wang, Zhihui, Birch, Christina M., Deisboeck, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430419/
https://ncbi.nlm.nih.gov/pubmed/18448237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biosystems.2008.03.002
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