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Expression of cell cycle regulator cdk2ap1 suppresses tumor cell phenotype by non-cell autonomous mechanisms

We evaluated the effect of expressing the cell cycle regulator cdk2ap1 in epithelial or stromal cell compartments to reduce SCC growth in vitro and in vivo. Cell autonomous and/or non-cell autonomous expression of cdk2ap1 reduced tumor growth and invasion and altered cell cycle, adhesion, invasion,...

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Detalhes bibliográficos
Main Authors: Zolochevska, Olga, Figueiredo, Marxa L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735612/
https://ncbi.nlm.nih.gov/pubmed/19515604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2009.05.001
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