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Effect of Linker Structure on Surface Density of Aptamer Monolayers and their Corresponding Protein Binding Efficiency

A systematic study is reported on the effect of linker size and its chemical composition toward ligand binding to a surface-immobilized aptamer, measured using surface plasmon resonance. The results, using thrombin as the model system, showed that as the number of thymidine (T) units in the linker i...

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Bibliografiset tiedot
Päätekijät: Balamurugan, Subramanian, Obubuafo, Anne, McCarley, Robin L., Soper, Steven A., Spivak, David A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735585/
https://ncbi.nlm.nih.gov/pubmed/18989937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac8009559
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