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Effect of Linker Structure on Surface Density of Aptamer Monolayers and their Corresponding Protein Binding Efficiency
A systematic study is reported on the effect of linker size and its chemical composition toward ligand binding to a surface-immobilized aptamer, measured using surface plasmon resonance. The results, using thrombin as the model system, showed that as the number of thymidine (T) units in the linker i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735585/ https://ncbi.nlm.nih.gov/pubmed/18989937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac8009559 |
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