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The G18V CRYGS mutation associated with human cataracts increases γS-crystallin sensitivity to thermal and chemical stress
γS-Crystallin, important in maintaining lens transparency, is a monomeric βγ-crystallin comprising two paired homologous domains, each with two Greek key motifs. An autosomal dominant cortical progressive cataract has been associated with a G18V mutation in human γS-crystallin. To investigate the mo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735583/ https://ncbi.nlm.nih.gov/pubmed/19558189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900467a |
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