Nanoparticle-Delivered Suicide Gene Therapy Effectively Reduces Ovarian Tumor Burden in Mice

There is currently no effective therapy for patients with advanced ovarian cancer. To address the need for a more effective treatment for this deadly disease, we conducted pre-clinical tests in ovarian tumor-bearing mice to evaluate the therapeutic efficacy of using a cationic biodegradable poly(β-a...

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Bibliographische Detailangaben
Hauptverfasser: Huang, Yu-Hung, Zugates, Gregory T., Peng, Weidan, Holtz, David, Dunton, Charles, Green, Jordan J., Hossain, Naushad, Chernick, Michael R., Padera, Robert F., Langer, Robert, Anderson, Daniel G., Sawicki, Janet A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735403/
https://ncbi.nlm.nih.gov/pubmed/19643734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0061
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