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Hypoxia limits antioxidant capacity in red blood cells by altering glycolytic pathway dominance
The erythrocyte membrane is a newly appreciated platform for thiol-based circulatory signaling, and it requires robust free thiol maintenance. We sought to define physiological constraints on erythrocyte antioxidant defense. Hemoglobin (Hb) conformation gates glycolytic flux through the hexose monop...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Federation of American Societies for Experimental Biology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735367/ https://ncbi.nlm.nih.gov/pubmed/19417084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-130666 |
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