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Identification of a major susceptibility locus for lethal graft-versus-host disease in MHC-matched mice

Graft-versus-host disease (GVHD) is the major cause of morbidity and mortality after allogeneic hematopoietic cell transplantation. From a genetic perspective, GVHD is a complex phenotypic trait. While it is understood that susceptibility results from interacting polymorphisms of genes encoding hist...

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Detalhes bibliográficos
Main Authors: Cao, Thai M., Lazzeroni, Laura C., Tsai, Schickwann, Pang, Wendy W., Kao, Amy, Camp, Nicola J., Thomas, Alun, Shizuru, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735236/
https://ncbi.nlm.nih.gov/pubmed/19525392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900454
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