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HP1 Proteins Form Distinct Complexes and Mediate Heterochromatic Gene Silencing by Non-Overlapping Mechanisms

HP1 proteins are a highly conserved family of eukaryotic proteins, which bind to methylated histone H3 lysine 9 (H3K9) and are required for heterochromatic gene silencing. In fission yeast, two HP1 homologs, Swi6 and Chp2, function in heterochromatic gene silencing, but their relative contribution t...

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Main Authors: Motamedi, Mohammad R., Erica Hong, Eun-Jin, Li, Xue, Gerber, Scott, Denison, Carilee, Gygi, Steven, Moazed, Danesh
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735125/
https://ncbi.nlm.nih.gov/pubmed/19111658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.10.026
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