NRAGE, a p75NTR adaptor protein, is required for developmental apoptosis in vivo

NRAGE (also known as Maged1, dlxin) is a member of the MAGE gene family that may play a role in the neuronal apoptosis that is regulated by the p75 neurotrophin receptor (p75NTR). To test this hypothesis in vivo, we generated NRAGE knockout mice and found that NRAGE deletion caused a defect in devel...

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Detalhes bibliográficos
Main Authors: Bertrand, Mathieu JM, Kenchappa, Rajappa S, Andrieu, David, Leclercq-Smekens, Michèle, Nguyen, Huu Ngoc Tuan, Carter, Bruce D, Muscatelli, Françoise, Barker, Philip A, De Backer, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735073/
https://ncbi.nlm.nih.gov/pubmed/18772898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2008.127
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