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Thio-mediated synthesis of derivatized N-linked glycopeptides using isonitrile chemistry

The reaction of oligosaccharide isonitriles with peptide thioacids in the presence of bulky thiophenol as activator to provide N-linked glycopeptides at room temperature is described.

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Autors principals: Wu, Xiangyang, Yuan, Yu, Li, Xuechen, Danishefsky, Samuel J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735058/
https://ncbi.nlm.nih.gov/pubmed/20161157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2009.06.005
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