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Induction of Cystine-Glutamate Transporter x(c )(-) by Human Immunodeficiency Virus Type 1 Transactivator Protein Tat in Retinal Pigment Epithelium
PURPOSE: The transactivator protein Tat encoded by the human immunodeficiency virus-1 (HIV-1) genome reduces glutathione levels in mammalian cells. Because the retina contains large amounts of glutathione, a study was undertaken to determine the influence of Tat on glutathione levels, γ-glutamyl tra...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735043/ https://ncbi.nlm.nih.gov/pubmed/15326101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.03-1355 |
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