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Intestinal Microbiota Regulate Xenobiotic Metabolism in the Liver

BACKGROUND: The liver is the central organ for xenobiotic metabolism (XM) and is regulated by nuclear receptors such as CAR and PXR, which control the metabolism of drugs. Here we report that gut microbiota influences liver gene expression and alters xenobiotic metabolism in animals exposed to barbi...

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Hlavní autoři: Björkholm, Britta, Bok, Chek Mei, Lundin, Annelie, Rafter, Joseph, Hibberd, Martin Lloyd, Pettersson, Sven
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734986/
https://ncbi.nlm.nih.gov/pubmed/19742318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006958
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