Intestinal Microbiota Regulate Xenobiotic Metabolism in the Liver

BACKGROUND: The liver is the central organ for xenobiotic metabolism (XM) and is regulated by nuclear receptors such as CAR and PXR, which control the metabolism of drugs. Here we report that gut microbiota influences liver gene expression and alters xenobiotic metabolism in animals exposed to barbi...

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Detaylı Bibliyografya
Asıl Yazarlar: Björkholm, Britta, Bok, Chek Mei, Lundin, Annelie, Rafter, Joseph, Hibberd, Martin Lloyd, Pettersson, Sven
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2009
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734986/
https://ncbi.nlm.nih.gov/pubmed/19742318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006958
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