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Intestinal Microbiota Regulate Xenobiotic Metabolism in the Liver
BACKGROUND: The liver is the central organ for xenobiotic metabolism (XM) and is regulated by nuclear receptors such as CAR and PXR, which control the metabolism of drugs. Here we report that gut microbiota influences liver gene expression and alters xenobiotic metabolism in animals exposed to barbi...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2734986/ https://ncbi.nlm.nih.gov/pubmed/19742318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006958 |
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