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RB Activity Alters Checkpoint Response and Chemosensitivity in Lung Cancer Lines

BACKGROUND: The retinoblastoma tumor suppressor (RB) is a key regulator of cell cycle progression and is functionally inactivated in the majority of human non-small cell lung cancers (NSCLC). The specific influence of RB on therapeutic response in NSCLC remains elusive. MATERIALS AND METHODS: We inv...

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Bibliografiske detaljer
Main Authors: Reed, Michael F., Zagorski, William A., Knudsen, Erik S.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734970/
https://ncbi.nlm.nih.gov/pubmed/17640669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2007.03.038
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