Adenovector GAD65 gene delivery into the rat trigeminal ganglion produces orofacial analgesia

BACKGROUND: Our goal is to use gene therapy to alleviate pain by targeting glial cells. In an animal model of facial pain we tested the effect of transfecting the glutamic acid decarboxylase (GAD) gene into satellite glial cells (SGCs) of the trigeminal ganglion by using a serotype 5 adenovector wit...

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Autori principali: Vit, Jean-Philippe, Ohara, Peter T, Sundberg, Christopher, Rubi, Blanca, Maechler, Pierre, Liu, Chunyan, Puntel, Mariana, Lowenstein, Pedro, Castro, Maria, Jasmin, Luc
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734545/
https://ncbi.nlm.nih.gov/pubmed/19656360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-5-42
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