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Silencing the Kir4.1 Potassium Channel Subunit in Satellite Glial Cells of the Rat Trigeminal Ganglion Results in Pain-Like Behavior in the Absence of Nerve Injury

Growing evidence suggests that changes in the ion buffering capacity of glial cells can give rise to neuropathic pain. In the CNS, potassium ion (K(+)) buffering is dependent on the glia-specific inward rectifying K(+) channel Kir4.1. We recently reported that the satellite glial cells that surround...

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Autori principali: Vit, Jean-Philippe, Ohara, Peter T., Bhargava, Aditi, Kelley, Kanwar, Jasmin, Luc
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533133/
https://ncbi.nlm.nih.gov/pubmed/18417695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5053-07.2008
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