Distinct kinetics of human DNA ligases I, IIIα, IIIβ, and IV reveal direct DNA sensing ability and differential physiological functions in DNA repair

The three human LIG genes encode polypeptides that catalyze phosphodiester bond formation during DNA replication, recombination and repair. While numerous studies have identified protein partners of the human DNA ligases (hLigs), there has been little characterization of the catalytic properties of...

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Hlavní autoři: Chen, Xi, Ballin, Jeff D., Della-Maria, Julie, Tsai, Miaw-Sheue, White, Elizabeth J., Tomkinson, Alan E., Wilson, Gerald M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734511/
https://ncbi.nlm.nih.gov/pubmed/19589734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.06.002
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