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Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins

Understanding the energetics of molecular interactions is fundamental to all of the central quests of structural biology including structure prediction and design, mapping evolutionary pathways, learning how mutations cause disease, drug design, and relating structure to function. Hydrogen-bonding i...

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Autori principali: HyunJoong Joh, Nathan, Min, Andrew, Faham, Salem, Whitelegge, Julian P, Yang, Duan, Woods, Virgil L., Bowie, James U.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734483/
https://ncbi.nlm.nih.gov/pubmed/18500332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06977
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