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Approaches for Studying PMR1 Endonuclease-mediated mRNA Decay

While most eukaryotic mRNAs are degraded by exonucleases acting on either end of the molecule a subset of mRNAs undergo endonuclease cleavage within the mRNA body. Endonuclease cleavage can be activated by cellular stress, extracellular signals or by ribosome stalling, as might occur at a premature...

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Main Authors: Otsuka, Yuichi, Schoenberg, Daniel R.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734451/
https://ncbi.nlm.nih.gov/pubmed/19111180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0076-6879(08)02613-X
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