Characterization and Interlaboratory Comparison of a Gene Expression Signature for Differentiating Genotoxic Mechanisms

The genotoxicity testing battery is highly sensitive for detection of chemical carcinogens. However, it features a low specificity and provides only limited mechanistic information required for risk assessment of positive findings. This is especially important in case of positive findings in the in...

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Hlavní autoři: Ellinger-Ziegelbauer, Heidrun, Fostel, Jennifer M., Aruga, Chinami, Bauer, Daniel, Boitier, Eric, Deng, Shibing, Dickinson, Donna, Le Fevre, Anne-Celine, Fornace, Albert J., Grenet, Olivier, Gu, Yizhong, Hoflack, Jean-Christophe, Shiiyama, Masako, Smith, Roger, Snyder, Ronald D., Spire, Catherine, Tanaka, Gotaro, Aubrecht, Jiri
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
Genetic Toxicology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734310/
https://ncbi.nlm.nih.gov/pubmed/19465456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp103
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