ZNF93 Increases Resistance to ET-743 (Trabectedin; Yondelis®) and PM00104 (Zalypsis®) in Human Cancer Cell Lines

BACKGROUND: ET-743 (trabectedin, Yondelis®) and PM00104 (Zalypsis®) are marine derived compounds that have antitumor activity. ET-743 and PM00104 exposure over sustained periods of treatment will result in the development of drug resistance, but the mechanisms which lead to resistance are not yet un...

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Detalhes bibliográficos
Main Authors: Duan, Zhenfeng, Choy, Edwin, Harmon, David, Yang, Cao, Ryu, Keinosuke, Schwab, Joseph, Mankin, Henry, Hornicek, Francis J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734182/
https://ncbi.nlm.nih.gov/pubmed/19742314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006967
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