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Epidermal growth factor-stimulated extravillous cytotrophoblast motility is mediated by the activation of PI3-K, Akt and both p38 and p42/44 mitogen-activated protein kinases

BACKGROUND: Trophoblast invasion is a temporally and spatially regulated scheme of events that can dictate pregnancy outcome. Evidence suggests that the potent mitogen epidermal growth factor (EGF) regulates cytotrophoblast (CTB) differentiation and invasion during early pregnancy. METHODS AND RESUL...

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מידע ביבליוגרפי
Main Authors: LaMarca, Heather L., Dash, Philip R., Vishnuthevan, Keshika, Harvey, Evelyn, Sullivan, Deborah E., Morris, Cindy A., Whitley, Guy St. J.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733823/
https://ncbi.nlm.nih.gov/pubmed/18487214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/den178
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