Epidermal growth factor-stimulated extravillous cytotrophoblast motility is mediated by the activation of PI3-K, Akt and both p38 and p42/44 mitogen-activated protein kinases

BACKGROUND: Trophoblast invasion is a temporally and spatially regulated scheme of events that can dictate pregnancy outcome. Evidence suggests that the potent mitogen epidermal growth factor (EGF) regulates cytotrophoblast (CTB) differentiation and invasion during early pregnancy. METHODS AND RESUL...

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Detalhes bibliográficos
Main Authors: LaMarca, Heather L., Dash, Philip R., Vishnuthevan, Keshika, Harvey, Evelyn, Sullivan, Deborah E., Morris, Cindy A., Whitley, Guy St. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733823/
https://ncbi.nlm.nih.gov/pubmed/18487214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/den178
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