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An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity

A highly heritable and reproducible measure of asthma severity is baseline pulmonary function. Pulmonary function is largely determined by airway smooth muscle (ASM) tone and contractility. The large conductance, voltage and calcium-activated potassium (BK) channel negatively regulates smooth muscle...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Seibold, Max A., Wang, Bin, Eng, Celeste, Kumar, Gunjan, Beckman, Kenneth B., Sen, Saunak, Choudhry, Shweta, Meade, Kelley, Lenoir, Michael, Watson, H. Geoffrey, Thyne, Shannon, Williams, L. Keoki, Kumar, Rajesh, Weiss, Kevin B., Grammer, Leslie C., Avila, Pedro C., Schleimer, Robert P., Burchard, Esteban González, Brenner, Robert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733805/
https://ncbi.nlm.nih.gov/pubmed/18535015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn168
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