Genetic ancestry modifies pharmacogenetic gene–gene interaction for asthma

OBJECTIVE: A recent admixture mapping analysis identified interleukin 6 (IL6) and IL6 receptor (IL6R) as candidate genes for inflammatory diseases. In the airways during allergic inflammation, IL6 signaling controls the production of proinflammatory and anti-inflammatory factors. In addition, albute...

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Detalhes bibliográficos
Main Authors: Corvol, Harriet, De Giacomo, Anthony, Eng, Celeste, Seibold, Max, Ziv, Elad, Chapela, Rocio, Rodriguez-Santana, Jose R., Rodriguez-Cintron, William, Thyne, Shannon, Watson, H. Geoffrey, Meade, Kelley, LeNoir, Michael, Avila, Pedro C., Choudhry, Shweta, Burchard, Esteban Gonz!lez
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768127/
https://ncbi.nlm.nih.gov/pubmed/19503017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32832c440e
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