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Copper deficiency alters the neurochemical profile of developing rat brain

Copper deficiency is associated with impaired brain development and mitochondrial dysfunction. Perinatal copper deficiency was produced in Holtzman rats. In vivo proton NMR spectroscopy was used to quantify 18 cerebellar and hippocampal metabolites on postnatal day 21 (P21). Copper status was evalua...

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Bibliographic Details
Main Authors: Gybina, Anna A., Tkac, Ivan, Prohaska, Joseph R.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733331/
https://ncbi.nlm.nih.gov/pubmed/19356314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/147683009X423265
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