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Copper deficiency alters the neurochemical profile of developing rat brain

Copper deficiency is associated with impaired brain development and mitochondrial dysfunction. Perinatal copper deficiency was produced in Holtzman rats. In vivo proton NMR spectroscopy was used to quantify 18 cerebellar and hippocampal metabolites on postnatal day 21 (P21). Copper status was evalua...

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Detalhes bibliográficos
Main Authors: Gybina, Anna A., Tkac, Ivan, Prohaska, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733331/
https://ncbi.nlm.nih.gov/pubmed/19356314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/147683009X423265
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