Urothelial transdifferentiation to prostate epithelia is mediated by paracrine TGF-β signaling

The embryonic urogenital sinus mesenchyme (UGM) induces prostate epithelial morphogenesis in development. The molecular signals that drive UGM-mediated prostatic induction have not been defined. We hypothesized that the TGF-β signaling directed the prostatic induction. UGM from TGF-β type II recepto...

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Main Authors: Li, Xiaohong, Wang, Yongqing, Sharif-Afshar, Ali-Reza, Uwamariya, Consolate, Yi, Andrew, Ishii, Kenichiro, Hayward, Simon W., Matusik, Robert J., Bhowmick, Neil A.
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733217/
https://ncbi.nlm.nih.gov/pubmed/19281768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diff.2008.09.012
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