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Methylation is less abundant in BRCA1-associated compared with sporadic breast cancer
Background: Promoter methylation is a common epigenetic mechanism to silence tumor suppressor genes during breast cancer development. We investigated whether BRCA1-associated breast tumors show cancer-predictive methylation patterns similar to those found in sporadic tumors. Patients and methods: Qu...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2733079/ https://ncbi.nlm.nih.gov/pubmed/18647968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdn409 |
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