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Power for Genetic Association Study of Human Longevity Using the Case-Control Design

The efficiency of the popular case-control design in gene-longevity association studies needs to be verified because, different from a binary trait, longevity represents only the extreme end of the continuous life span distribution without a clear cutoff for defining the phenotype. In this paper, th...

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Detalhes bibliográficos
Main Authors: Tan, Qihua, Zhao, Jing Hua, Zhang, Dongfeng, Kruse, Torben A., Christensen, Kaare
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732955/
https://ncbi.nlm.nih.gov/pubmed/18756013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwn205
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