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Evolutionary and functional insights into the mechanism underlying high-altitude adaptation of deer mouse hemoglobin

Adaptive modifications of heteromeric proteins may involve genetically based changes in single subunit polypeptides or parallel changes in multiple genes that encode distinct, interacting subunits. Here we investigate these possibilities by conducting a combined evolutionary and functional analysis...

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Autors principals: Storz, Jay F., Runck, Amy M., Sabatino, Stephen J., Kelly, John K., Ferrand, Nuno, Moriyama, Hideaki, Weber, Roy E., Fago, Angela
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732835/
https://ncbi.nlm.nih.gov/pubmed/19667207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905224106
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