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Evolutionary and functional insights into the mechanism underlying high-altitude adaptation of deer mouse hemoglobin

Adaptive modifications of heteromeric proteins may involve genetically based changes in single subunit polypeptides or parallel changes in multiple genes that encode distinct, interacting subunits. Here we investigate these possibilities by conducting a combined evolutionary and functional analysis...

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Detalles Bibliográficos
Main Authors: Storz, Jay F., Runck, Amy M., Sabatino, Stephen J., Kelly, John K., Ferrand, Nuno, Moriyama, Hideaki, Weber, Roy E., Fago, Angela
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732835/
https://ncbi.nlm.nih.gov/pubmed/19667207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905224106
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