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In vivo manipulation of gene expression in non-human primates using lentiviral vectors as delivery vehicles
Nonhuman primates (NHPs) are an invaluable resource for the study of genetic regulation of disease mechanisms. The main disadvantage of using NHPs as a preclinical model of human disease is the difficulty of manipulating the monkey genome using conventional gene modifying strategies. Lentiviruses of...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732747/ https://ncbi.nlm.nih.gov/pubmed/19559089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.06.004 |
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