A computational approach identifies two regions of Hepatitis C Virus E1 protein as interacting domains involved in viral fusion process

BACKGROUND: The E1 protein of Hepatitis C Virus (HCV) can be dissected into two distinct hydrophobic regions: a central domain containing an hypothetical fusion peptide (FP), and a C-terminal domain (CT) comprising two segments, a pre-anchor and a trans-membrane (TM) region. In the currently accepte...

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Main Authors: Bruni, Roberto, Costantino, Angela, Tritarelli, Elena, Marcantonio, Cinzia, Ciccozzi, Massimo, Rapicetta, Maria, El Sawaf, Gamal, Giuliani, Alessandro, Ciccaglione, Anna Rita
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732612/
https://ncbi.nlm.nih.gov/pubmed/19640267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-9-48
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