A computational approach to identify point mutations associated with occult hepatitis B: significant mutations affect coding regions but not regulative elements of HBV

BACKGROUND: Occult Hepatitis B Infection (OBI) is characterized by absence of serum HBsAg and persistence of HBV-DNA in liver tissue, with low to undetectable serum HBV-DNA. The mechanisms underlying OBI remain to be clarified. To evaluate if specific point mutations of HBV genome may be associated...

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Detalhes bibliográficos
Main Authors: Bruni, Roberto, Prosperi, Mattia, Marcantonio, Cinzia, Amadori, Alessandra, Villano, Umbertina, Tritarelli, Elena, Presti, Alessandra Lo, Ciccozzi, Massimo, Ciccaglione, Anna R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170640/
https://ncbi.nlm.nih.gov/pubmed/21824402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-394
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