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Supervised principal component analysis for gene set enrichment of microarray data with continuous or survival outcomes
Motivation: Gene set analysis allows formal testing of subtle but coordinated changes in a group of genes, such as those defined by Gene Ontology (GO) or KEGG Pathway databases. We propose a new method for gene set analysis that is based on principal component analysis (PCA) of genes expression valu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732277/ https://ncbi.nlm.nih.gov/pubmed/18753155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btn458 |
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