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PATHWAY-BASED ANALYSIS FOR GENOME-WIDE ASSOCIATION STUDIES USING SUPERVISED PRINCIPAL COMPONENTS
Many complex diseases are influenced by genetic variations in multiple genes, each with only a small marginal effect on disease susceptibility. Pathway analysis, which identifies biological pathways associated with disease outcome, has become increasingly popular for genome-wide association studies...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3480088/ https://ncbi.nlm.nih.gov/pubmed/20842628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20532 |
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