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Multimarker analysis and imputation of multiple platform pooling-based genome-wide association studies

Summary: For many genome-wide association (GWA) studies individually genotyping one million or more SNPs provides a marginal increase in coverage at a substantial cost. Much of the information gained is redundant due to the correlation structure inherent in the human genome. Pooling-based GWA studie...

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Hlavní autoři: Homer, Nils, Tembe, Waibhav D., Szelinger, Szabolcs, Redman, Margot, Stephan, Dietrich A., Pearson, John V., Nelson, Stanley F., Craig, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732219/
https://ncbi.nlm.nih.gov/pubmed/18617537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btn333
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