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Hydrolysis of cis- and trans-Epoxyeicosatrienoic Acids by Rat Red Blood Cells

Erythrocytes serve as reservoirs for cis- and trans-epoxyeicosatrienoic acids (EETs). Incubation of rat red blood cells (RBCs) with cis- and trans-EETs produces threo- and erythro-dihydroxyeicosatrienoic acids, respectively. The V(max) of EET hydrolysis by rat intact RBCs (2.35 ± 0.24 pmol/min/10(8)...

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Detalhes bibliográficos
Main Authors: Jiang, Houli, Zhu, Angela G., Mamczur, Magdalena, Morisseau, Christophe, Hammock, Bruce D., Falck, John R., McGiff, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732189/
https://ncbi.nlm.nih.gov/pubmed/18445784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.107.134858
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