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Vitamin C activation of the biosynthesis of epoxyeicosatrienoic acids

The cardiovascular effects of vitamin C (VitC) could be mediated by epoxyeicosatrienoic acids (EETs). We aimed to study the mechanism of VitC-dependent microsomal formation of cis- and trans-EETs and the regulation of EET levels in rat isolated perfused kidneys and in vivo. VitC biphasically stimula...

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Detalhes bibliográficos
Main Authors: Jiang, Houli, Harrison, Fiona E., Jain, Kavita, Benjamin, Samantha, May, James M., Graves, Joan P., Zeldin, Darryl C., Falck, John R., Hammock, Bruce D., McGiff, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958942/
https://ncbi.nlm.nih.gov/pubmed/24660109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4236/abb.2012.33029
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