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miRiad roles for the miR-17-92 cluster in development and disease

MicroRNAs (miRNAs) encoded by the miR-17-92 cluster and its paralogs are known to act as oncogenes. Expression of these miRNAs promotes cell proliferation, suppresses apoptosis of cancer cells and induces tumor angiogenesis. New work reveals essential functions for these miRNAs not only in tumor for...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Mendell, Joshua T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732113/
https://ncbi.nlm.nih.gov/pubmed/18423194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.04.001
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