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miRiad roles for the miR-17-92 cluster in development and disease

MicroRNAs (miRNAs) encoded by the miR-17-92 cluster and its paralogs are known to act as oncogenes. Expression of these miRNAs promotes cell proliferation, suppresses apoptosis of cancer cells and induces tumor angiogenesis. New work reveals essential functions for these miRNAs not only in tumor for...

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Detalles Bibliográficos
Autor Principal: Mendell, Joshua T.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732113/
https://ncbi.nlm.nih.gov/pubmed/18423194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.04.001
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