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Biochemical characterization of two functional human liver acyl-CoA oxidase isoforms 1a and 1b encoded by a single gene

Human acyl-CoA oxidase 1 (ACOX1) is a rate-limiting enzyme in peroxisomal fatty acids β-oxidation and its deficiency is associated with a lethal, autosomal ressive disease, called pseudoneonatal-adrenoleukodystrophy. Two mRNA variants, transcribed from a single gene encode ACOX1a or ACOX1b isoforms...

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Detalhes bibliográficos
Main Authors: Oaxaca-Castillo, David, Andreoletti, Pierre, Vluggens, Aurore, Yu, Sangtao, van Veldhoven, Paul P., Reddy, Janardan K., Cherkaoui-Malki, Mustapha
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732019/
https://ncbi.nlm.nih.gov/pubmed/17603022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.06.059
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