Impaired Estrogen Feedback and Infertility in Female Mice with Pituitary-Specific Deletion of Estrogen Receptor Alpha (ESR1)

Mice lacking estrogen receptor alpha in the pituitary gonadotroph (PitEsr1KO) were generated to determine the physiologic role of pituitary estrogen signaling in the reproductive axis. PitEsr1KO female mice are subfertile or infertile and have elevated levels of serum luteinizing hormone (LH) and LH...

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Bibliografski detalji
Glavni autori: Singh, Surya P., Wolfe, Andrew, Ng, Yewade, DiVall, Sara A., Buggs, Colleen, Levine, Jon E., Wondisford, Fredric E., Radovick, Sally
Format: Artigo
Jezik:Inglês
Izdano: Society for the Study of Reproduction, Inc. 2009
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731984/
https://ncbi.nlm.nih.gov/pubmed/19439729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.075259
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