Impaired Estrogen Feedback and Infertility in Female Mice with Pituitary-Specific Deletion of Estrogen Receptor Alpha (ESR1)

Mice lacking estrogen receptor alpha in the pituitary gonadotroph (PitEsr1KO) were generated to determine the physiologic role of pituitary estrogen signaling in the reproductive axis. PitEsr1KO female mice are subfertile or infertile and have elevated levels of serum luteinizing hormone (LH) and LH...

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Détails bibliographiques
Auteurs principaux: Singh, Surya P., Wolfe, Andrew, Ng, Yewade, DiVall, Sara A., Buggs, Colleen, Levine, Jon E., Wondisford, Fredric E., Radovick, Sally
Format: Artigo
Langue:Inglês
Publié: Society for the Study of Reproduction, Inc. 2009
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731984/
https://ncbi.nlm.nih.gov/pubmed/19439729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.075259
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