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Gas6 - Axl receptor signaling is regulated by glucose in vascular smooth muscle cells

OBJECTIVE: The receptor tyrosine kinase Axl and its ligand Gas6 are involved in the development of renal diabetic disease. In vascular smooth muscle cells (VSMC) Axl is activated by reactive oxygen species and stimulates migration and cell survival, suggesting a role for Axl in the vascular complica...

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Bibliografische gegevens
Hoofdauteurs: Cavet, Megan E., Smolock, Elaine M., Ozturk, Oktay H., World, Cameron, Pang, Jinjiang, Konishi, Atsushi, Berk, Bradford C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731942/
https://ncbi.nlm.nih.gov/pubmed/18292389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.162693
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