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Gas6 - Axl receptor signaling is regulated by glucose in vascular smooth muscle cells

OBJECTIVE: The receptor tyrosine kinase Axl and its ligand Gas6 are involved in the development of renal diabetic disease. In vascular smooth muscle cells (VSMC) Axl is activated by reactive oxygen species and stimulates migration and cell survival, suggesting a role for Axl in the vascular complica...

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Detalhes bibliográficos
Main Authors: Cavet, Megan E., Smolock, Elaine M., Ozturk, Oktay H., World, Cameron, Pang, Jinjiang, Konishi, Atsushi, Berk, Bradford C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731942/
https://ncbi.nlm.nih.gov/pubmed/18292389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.162693
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