A carregar...

In situ growth of a stoichiometric PEG-like conjugate at a protein's N-terminus with significantly improved pharmacokinetics

The challenge in the synthesis of protein-polymer conjugates for biological applications is to synthesize a stoichiometric (typically 1:1) conjugate of the protein with a monodisperse polymer, with good retention of protein activity, significantly improved pharmacokinetics and increased bioavailabil...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gao, Weiping, Liu, Wenge, Mackay, J. Andrew, Zalutsky, Michael R., Toone, Eric J., Chilkoti, Ashutosh
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731796/
https://ncbi.nlm.nih.gov/pubmed/19706892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904378106
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!