Knowledge based identification of essential signaling from genome-scale siRNA experiments

BACKGROUND: A systems biology interpretation of genome-scale RNA interference (RNAi) experiments is complicated by scope, experimental variability and network signaling robustness. Over representation approaches (ORA), such as the Hypergeometric or z-score, are an established statistical framework u...

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Autori principali: Bankhead, Armand, Sach, Iliana, Ni, Chester, LeMeur, Nolwenn, Kruger, Mark, Ferrer, Marc, Gentleman, Robert, Rohl, Carol
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731733/
https://ncbi.nlm.nih.gov/pubmed/19653913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-3-80
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