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Mycolic acid cyclopropanation is essential for viability, drug resistance and cell wall integrity of Mycobacterium tuberculosis
Mycobacterium tuberculosis Infection remains a major global health problem complicated by escalating rates of antibiotic resistance. Despite the established role of mycolic acid cyclopropane modification in pathogenesis, the feasibility of targeting this enzyme family for antibiotic development is u...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2731493/ https://ncbi.nlm.nih.gov/pubmed/19477414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.04.001 |
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